Protein Encyclopedia / Human Protein Database.

Advances in Molecular technology have made data generation much easier, but processing it and interpreting observations are now the major hurdles in science today.Johns Hopkins Institute of Genetic Medicine has compiled the Database of Human Proteins which contains the experimental information about human proteins.Human Proteinpedia contains information on when and where specific proteins are expressed or not, including in cells and tissues from diseases such as cancers. Human Proteinpedia allows any researcher to contribute and edit their data as their research progresses.

Highlights of Proteinpedia ...

Number of contributing labs	71
Number of Experiments	2,695
Protein Entries	15,231
Peptide Identifications	1,851,124
MS/MS Spectra	4,567,235
Protein Expression	138,487
Post-translational modifications	17,108
Protein-protein interactions	31,476
Subcellular localization	2,906

Visit ProteinPedia

1. http://www.humanproteinpedia.org/

Bioinformatics Softwares / Tools - Gene Prediction

Gene prediction / Gene finding softwares:

After sequencing a genome of a organism the next and the most important step is to predict the genes in the genome. Homology Search method (Ex:BLAST)is a very simple and straight forward method to predict genes.

• GLIMMER - To identify coding regions in microbial DNA.
  


• GeneScan - To predict complete gene structures, including exons, introns, promoter and poly-adenylation signals, in genomic sequences
  


• GeneMark - For finding genes in bacterial DNA sequences.
  


• WebGene
  - Web interface for several coding region recognition programs.

Bioinformatics Market Growth - Year wise

Bioinformatics Opportunities in India

Outsourcing to India, compared to other developed countries, offers about 30-40% costs savings in overall drug discovery research, and close to 60% cost savings when outsourcing core bioinformatics services. This is due to the lower wage costs for skilled manpower, and lower infrastructure costs.

The Indian bioinformatics market has grown from $18 million in 2003-04 to $35 million in 2006-07, at a CAGR of 25%. Interestingly, owing to low local demand, $32 million or about 90% of bioinformatics revenues in India are derived from outsourcing activities. "Local demand for bioinformatics services is low due to low investment in new drug discovery. Even though research investments of life sciences companies are increasing, they are still small compared to global standards" says Ashutosh Mundkur, VBU Life Sciences, Service Offerings, Satyam Computer Services Ltd.

The Indian bioinformatics outsourcing services opportunity is estimated to grow at 25% per annum during 2007-2010 raising its share of the global market from 1.4% in 2007 to 1.7% in 2010. These estimates are made based on the current plans of Indian vendors, as well as considering the impact of scarcity in human resources. Improved availability of skilled workers could help take growth rates higher. Similarly, positive actions by the Indian government to enhance IP rights could also help raise growth.

Indian Bioinformatics Market:

Pharmaceutical companies are under constant pressure to develop new “blockbuster” drugs to replace older ones that are going off patent. With costs to launch a new drug crossing $1 billion and the number of drugs approved for commercial launch decreasing, pharmaceutical companies are increasingly looking at biotechnology to deliver results.

The Indian bioinformatics industry comprises vendors with origins in the life sciences domain or the IT domain. We estimate that there are about 45-50 companies active in the bioinformatics segment in India. Of these, about 35 are involved in the development of software tools, database solutions and providing bioinformatics services; the remaining largely into marketing third party products and services.

2005 Report:

The global bioinformatics market is currently estimated at about $1.4 billion (€1.1 billion). It is expected to grow at an average annual growth rate of 15.8 per cent to reach nearly $3 billion by 2010

Pharmaceutical companies are expected to increase their R&D expenditure in the future. A major portion of this R&D spending is expected to go into bioinformatics. Global drug discovery spending is estimated to increase from $19.6 billion in 2002 to $25.1 billion in 2006.

Scientists are acquiring genomics data through the use of techniques such as amplification, DNA microarray expression, real-time PCR and genotyping. Instrumentation, hardware and software are then required to analyse, integrate and transmit this vast amount of data, which has resulted in significant IT challenges for those in the field.

The segment is estimated to grow at an average annual growth rate (AAGR) of 21.2 per cent from $444.7 million in 2005 to $1.16 billion in 2010. Growth in the genomics-based content will be the key driver for the rise in genomics-based analysis software and services segment.

References:
1. Drug Researcher

2. PharmaAsia

Bioinformatics Books Collection / Bioinformatics Book Collection.

Visit 123Bioinformatics.com for more Updates

• Advanced Data Mining Technologies in Bioinformatics


• Advances in Molecular Bioinformatics


• An Introduction to Bioinformatics Algorithms


• Artificial Intelligence and Heuristic Methods in Bioinformatics


• Beginning Perl for Bioinformatics


• Bioinformatics: A Modern Approach


• Bioinformatics and Computational Biology Solutions Using R and Bioconductor


• Bioinformatics: An Introduction


• Bioinformatics: A Practical Approach


• Bioinformatics Basics: Applications in Biological Science and Medicine


• Bioinformatics Biocomputing and Perl: An Introduction to Bioinformatics Computing Skills


• Bioinformatics Computing


• Bioinformatics: Databases and Systems


• Bioinformatics for Geneticists


• Bioinformatics Methods and Protocols


• Bioinformatics of Genome Regulation and Structure II


• Bioinformatics: Sequence and Genome Analysis


• Bioinformatics:Sequence and Genome Analysis


• Bioinformatics Software Engineering: Delivering Effective Applications


• Bioinformatics Technologies


• Bioinformatics: the machine learning approach


• Computational Systems Bioinformatics


• Computational Text Analysis For Functional Genomics And Bioinformatics


• Data Mining in Bioinformatics


• Data Mining: Multimedia, Soft Computing, and Bioinformatics


• Developing Bioinformatics Computer Skills


• Digital Code of Life: how bioinformatics is revolutionizing science, medicine, and business


• Emergent Computation: Emphasizing Bioinformatics


• Essays in Bioinformatics


• Essential Bioinformatics


• Essentials of Genomics and Bioinformatics


• Evolutionary Computation in Bioinformatics


• Genomic Perl: From Bioinformatics Basics to Working Code


• Hidden Markov Models for Bioinformatics


• Immunological Bioinformatics


• Introduction to Bioinformatics: A Theoretical and Practical Approach


• Introduction to Mathematical Methods in Bioinformatics


• Mastering Perl for Bioinformatics


• Microarray Bioinformatics


• Molecular Bioinformatics: Algorithms and applications


• Practical Bioinformatics


• Probabilistic Modeling in Bioinformatics and Medical Informatics


• Protein Bioinformatics: an algorithmic approach to sequence and structure analysis


• Statistical Methods in Bioinformatics: an introduction


• The New Avenues in Bioinformatics


• The Ten Most Wanted Solutions in Protein Bioinformatics


• XML for Bioinformatics

Bioinformatics openings in Southeast Asia / Bioinformatics Jobs.

Malaysia is one of the fastest growing economic powers in Asia pacific. Cyberjaya is the IT hub of Malaysia with hundreds of software companies. Follow the below link to apply for Bioinformatics and IT jobs in CyberJaya, Malaysia.

http://www.cyberjaya-jobs.com/

123 Bioinformatics Team