ScalaBLAST - For High End genome analysis

Analyzing the whole genome is still a time taking process. A new computational tool developed at the Department of Energy's Pacific Northwest National Laboratory is speeding up our understanding of the machinery of life – bringing us one step closer to curing diseases, finding safer ways to clean the environment and protecting the country against biological threats.

ScalaBLAST is a sophisticated "sequence alignment tool" that can divide the work of analyzing biological data into manageable fragments so large data sets can run on many processors simultaneously. The technology means large-scale problems – such as the analysis of an organism – can be solved in minutes, rather than weeks.

Using ScalaBLAST, researchers can manage the large influx of data resulting from new questions that arise during human genome research. Prior to this new tool, it took researchers 10 days to analyze one organism. Now, researchers can analyze 13 organisms within nine hours, making the time-to-solution hundreds of times faster.

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ScalaBLAST

PyroBayes - Analyze 500,000 Sequences in 10 Mins.

Human Genome and Annotation project took more than a decade to complete. Boston College Biologist Gabor Marth and his research team have developed software that can analyze half a million DNA sequences in 10 minutes.
The Marth laboratory's proprietary PyroBayes software is one of a new breed of computer programs able to accurately process the mountains of genome data flowing from the latest generation of gene decoding machines, which have placed a premium on computational speed and accuracy in data-crunching fields known as bioinformatics and high-throughput biology, said Marth, an associate professor of Biology.

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Pyrobayes: an improved base caller for SNP discovery in pyrosequences.

The MarthLab : PyroBayes