Tuesday, April 1, 2008

What is Bioinformatics

What is bioinformatics ?

It's method to predict the biological outcomes before anyone go for full fledged research. It's a method to compare the biological data. Ex: sequence analysis. It's a way to predict or solve the protein structure.
It's the only way for PERSONALIZED MEDICINE in this post genomic era. It's the method to do comparative genomics and predict the Human homolog genes in other species.
It's the method to annotate the newly sequenced genomes.

How the biological problems can be predicted ?

We are living in the world of Computers. By analyzing the existing biological data using Information Technology we can predict the biological outcomes.

What is the HOTTEST branch of Bioinformaics in this post genomic era ?

Personalized medicine is the most hottest and fastest growing field. Personalized medicine can be achieved through bioinformatics only.

6 comments:

Pfern said...

Bioinformatics covers that, to some extent, but certainly not to validate the notion that personalized medicine it simple, or even at easy reach. Before we can step into personalized medicine there is a lot more to learn from nature itself.

Bioinformatics allows for discovery or knowledge acquisition in the Biomedical area, in a broad sense, by allowing the analysis of biological information at the appropriate scale, even if it is very large. By biological information we mean organized datasets of information coming mainly form laboratory instruments capabel of assessing the composition of biologically interesting molecules and their properties. Examples are nucleic acid (DNA,RNA) and amino acid (proteins, peptide) sequences, microarray data, proteomic data, etc.

Bioinformatics activities employ a lot of techniques that are transversal in science. Mathematics and in particular Statistics are used evrywhere. The same applies to algorithms, database management, computer and network technologies, etc.

Bioinformatician said...

Hi Pedro, Yes you are right.
But, cost of genotyping is getting cheaper everymonth. Researchers are aiming for $1000 genome sequencing.
In this genotyping era, labs are producing lots of "Genome Associated data". Doctors and Scientists are expecting more genetic association data to come out.
Once we have the enough data, Bioinformatics will play the crucial role. After the completion of Human genome project only Bioinformatics played the crucial role. Comparative genomics proved its power with the help of Bioinformatics.



data flow from the labs are at its peak.

Anonymous said...

All the best for the blog. I do understand your passion for bioinformatics. However I too believe that personalized medicine is still a utopian dream. As a clinician, I must say that bioinformatics so far has had less effect on clinical medicine than serendipity.

Anonymous said...

hello blogger...good job..

Anonymous said...

All the best

Settu Sridhar said...

hello bioinformatician,
yeah quite interesting blog..definitly very good one for the beginners. The information here are more general and looks like your personal statement. If u could still add more related information regarding bioinformatics and its roll in various disciplines like proteomics, microarray, genome annotation, comparative genomics, genome assembly,structural bioinformatics, RNA analyis, method development, database integration, regulatory networks and systems biology it will be a gr8 portal to know more generally about bioinformatics. i dont know whether it may in ur future perception it would be useful if u could post about IT level which a bioinformatician should possess and useful to pursue bioinformatics. expecting a lot to learn from this blog..these r just my suggestions..u may have ur own perception on maintaining this..all the best..keep posting..